Erythromycin derivatives

专利名称：Erythromycin derivatives发明人：Constantin Agouridas,Yannick

Benedetti,Jean-Francois Chantot,AlexisDenis,Odile Le Martret

申请号：US08/414503申请日：19950331公开号：US05656607A公开日：19970812

摘要：A compound selected from the group consisting of a compound of the formula##STR1## wherein R.sub.1 and R.sub.2 are individually selected from the group consistingof hydrogen and an optionally unsaturated hydrocarbon of up to 24 carbon atomsoptionally interrupted by at least one heteroatom selected from the group consisting ofoxygen, sulfur and nitrogen and optionally having at least one functional group or takentogether form ##STR2## and R'.sub.1 and R'.sub.2 are individually selected from thegroup consisting of hydrogen and an optionally unsaturated hydrocarbon of up to 23carbon atoms optionally interrupted by at least one heteroatom selected from thegroup consisting of nitrogen, oxygen and sulfur and optionally having at least onefunctional group, Z is hydrogen or acyl of an organic carboxylic acid of 1 to 18 carbonatoms and the wavy line indicates the 10-methyl may have R or S configuration or amixture of R+S and their non-toxic, pharmaceutically acceptable acid addition salts havingantibiotic properties.

申请人：ROUSSEL UCLAF

代理机构：Bierman, Muserlian and Lucas, LLP

更多信息请下载全文后查看