CYCLIC INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDRO

专利名称：CYCLIC INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1

发明人：RENZ, Martin,SCHUELE, Martin,XU, Zhenrong申请号：EP10721215.1申请日：20100430公开号：EP2424865A2公开日：20120307

摘要：This invention relates to novel compounds of the Formula Ik, Im1, Im2, Im5, In1,In2, In5, lo1, lo2, lo5, Ip1, Ip3, pharmaceutically acceptable salts thereof, and

pharmaceutical compositions thereof, which are useful for the therapeutic treatment ofdiseases associated with the modulation or inhibition of 11 β-HSD1 in mammals. Theinvention further relates to pharmaceutical compositions of the novel compounds andmethods for their use in the reduction or control of the production of Cortisol in a cell orthe inhibition of the conversion of cortisone to Cortisol in a cell.

申请人：Boehringer Ingelheim International GmbH,Vitae Pharmaceuticals, Inc.

地址：Binger Strasse 173 55216 Ingelheim am Rhein DE,502 West Office Center DriveFort Washington, PA 19034 US

国籍：DE,US

代理机构：Simpson, Mark Geoffrey

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