Stabilized Subtilisin Composition

专利名称：Stabilized Subtilisin Composition发明人：Lise Munch Mikkelsen,Francesco

Ponzini,Roberto Bisaccia,Renato Canevotti

申请号：US14129748申请日：20120629

公开号：US20140336098A1公开日：20141113

摘要：The conversion of a peptide aldehyde to a hydrosulfite adduct can be used toincrease the aqueous solubility in the purification of the peptide aldehydes.

Advantageously, this hydrosulfite adduct is itself effective as a subtilisin inhibitor andstabilizer and it can also stabilize a second enzyme if present. The hydrosulfite adduct iseffective as a subtilisin inhibitor, and it maintains its inhibitory and stabilizing effect in aliquid detergent during storage. Thus, use of the hydrosulfite adduct can avoid the costand time of converting it back to the peptide aldehyde and subsequent drying of thepeptide aldehyde can be saved, and this can avoid the inconvenience of handling thepeptide aldehyde in powder form or as a highly diluted aqueous solution.

申请人：Lise Munch Mikkelsen,Francesco Ponzini,Roberto Bisaccia,Renato Canevotti

地址：Roedovre DK,Corsico IT,Monte Giovanni IT,Concorezzo IT

国籍：DK,IT,IT,IT

更多信息请下载全文后查看